Fenbendazole is a medicine used to treat parasitic worm infections in animals and humans. It is also an effective cancer treatment and has been shown to decrease cancer cell growth in laboratory settings. It works by interfering with glucose intake, starving cancer cells of the energy they need to grow and multiply.
It is used to treat helminth infections
Fenbendazole is a broad-spectrum anthelmintic drug used to treat various helminth infections in poultry. It acts by targeting the benzimidazole group of parasites, which includes hookworms (Drontal Plus, Bayer Animal Health), whipworms (Fenbantel, Novartis), roundworms, and tapeworms such as Dipylidium caninum and Echinococcus spp. It is also effective against trichomoniasis.
It works by binding to beta-tubulin, a protein found in tiny tube-like structures called microtubules. These structures play a vital role in many cell functions, including division and reproduction. When fenbendazole binds to this protein, it interferes with the formation of the microtubules, preventing them from functioning properly.
In addition, fenbendazole was found to activate the p53 tumor suppressor gene and induce cell cycle arrest and apoptosis in 5-FU-sensitive cells. In particular, fenbendazole caused G2/M cell cycle arrest and apoptosis via p53-dependent and -independent pathways in colorectal cancer cells. In addition, fenbendazole induced ferroptosis, which is characterized by lipid peroxidation, in cells. This is a unique feature that may be associated with its anti-cancer activity.
It is used to treat cancer
Fenbendazole, an anthelmintic drug used to treat parasitic worm infestations since the 1970s, has been shown to be effective against a wide range of human cancers. It has been shown to reduce tumor size and halt progression in large B-cell lymphoma, renal cell carcinoma, and bladder cancer. It is also believed to help patients with metastatic cancers.
A recent study suggests that fenbendazole inhibits the growth of microtubules in cancer cells, which are necessary for cell structure. The researchers believe that if these microtubules are destroyed, cancer cells will be unable to survive. The findings support the growing scientific evidence that fenbendazole and other drugs in the benzimidazole family may have powerful cancer-fighting potential.
The anthelmintic drug has also been shown to interfere with the glucose uptake by cancer cells, starving them of the energy they need to grow and multiply. This effect was seen in both normal and 5-fluorouracil-resistant cancer cells. In addition, fenbendazole was able to cause apoptosis in 5-fluorouracil-resistant cancer cell lines without activating p53. This suggests that it could be an effective chemotherapeutic drug in combination with radiation therapy, surgery, berberine, and sodium dichloroacetate (DCA).
It is safe
Fenbendazole is an anthelmintic drug that is safe to use in humans. It is also a common treatment for parasitic infections, including pinworms, giardiasis, roundworms, hookworms, Taenia solium, and pulmonary paragonimiasis. It is a member of the benzimidazole family and exerts antiparasitic effects by binding to b-tubulin microtubule subunits and disrupting polymerization. This action is similar to that of vinca alkaloids and other cytotoxic anticancer agents.
This effect interferes with cancer cell growth and inhibits the cell’s ability to absorb glucose, which is necessary for survival. This results in a decrease in cancer cells both in laboratory settings and in living subjects.
Scientists have found that fenbendazole can be used with other chemotherapeutic agents to increase their efficacy against cancer. It can help reduce the side effects of chemotherapy and improve outcomes in patients with advanced disease. In addition, it can help prevent the recurrence of cancer after treatment. It has also been shown to suppress tumor growth and promote regression in a variety of cancer patients.
It is available without a prescription
Fenbendazole is a broad spectrum benzimidazole anthelmintic that destroys the microtubules of digestive cells, preventing helminths from growing. It is also known as an antiparasitic, and can be used to treat giardia, roundworms, hookworms, whipworms, and the tapeworm genus Taenia. It is available without a prescription in many countries. However, it is important to talk to your veterinarian before giving this medication to your pet. Your vet will help you determine the right dosage for your pet, and will also discuss any other medications your pet is taking.
It has been found in several scientific journals that fenbendazole may inhibit cancer cell growth. Although it has not been studied in humans for long-term use, it is commonly used as a veterinary medicine and is safe to take for extended periods of time.
Some patients self-administer fenbendazole in order to prevent or treat their cancer, and have reported success. This practice is discouraged by medical professionals because it can cause serious complications.fenbendazole for humans